Title of article
C1-Symmetric Aminosulfoximines as Ligands in Copper-Catalyzed Carbonyl-Ene Reactions
Author/Authors
Bolm، Carsten نويسنده , , Langner، Martin نويسنده , , Remy، Pauline نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-780
From page
781
To page
0
Abstract
Highly modular C1-symmetric aminosulfoximines were prepared and applied as chiral ligands in copper-catalyzed enantioselective carbonyl-ene reactions. The optimized system catalyzed the conversion of pyruvates and 1,1-disubstituted olefins yielding the corresponding hydroxy esters with high enantiomeric excesses (up to 91% ee) in moderate yields.
Keywords
Asymmetric catalysis , (alpha)-hydroxy esters , carbonyl-ene reactions , copper , sulfoximines
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110257
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