Title of article :
Automated Parallel Synthesis of a Protected Oligosaccharide Library Based upon the Structure of Dimeric Lewis X by One-Pot Sequential Glycosylation
Author/Authors :
Tanaka، Hiroshi نويسنده , , Takahashi، Takashi نويسنده , , Matoba، Nobuatsu نويسنده , , Tsukamoto، Hirokazu نويسنده , , Takimoto، Hisami نويسنده , , Yamada، Haruo نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
An efficient synthesis of a protected dimeric Lewis X epitope by two sequential one-pot glycosylations is described. Combinatorial synthesis of the dimeric Lewis X epitope derivatives by the one-pot glycosylation was accomplished utilizing an automated synthesizer to provide 12-protected oligosaccharides.
Keywords :
glycosyl fluoride , Lewis X , thioglycoside , automated synthesis , one-pot glycosylation