Title of article :
First total synthesis of tripdiolide
Author/Authors :
Bing Zhou، نويسنده , , Huanyu Tang، نويسنده , , Huijin Feng، نويسنده , , Yuanchao Li، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
The first total synthesis of tripdiolide 1 from the readily available abietic acid 3 in 22 steps is described and this synthesis furnishes a 5.8% overall yield of 1 with an average yield of 87%.
Keywords :
Total synthesis , Tripdiolide , Abietic acid , Tripterygium wilfordii Hook. f. , ? , ?-Unsaturated lactone ring
Journal title :
Tetrahedron
Journal title :
Tetrahedron