Title of article
A convergent synthesis of the [4.4]-spiroacetal-γ-lactones cephalosporolides E and F
Author/Authors
Margaret A. Brimble، نويسنده , , Orla C. Finch، نويسنده , , Amanda M. Heapy، نويسنده , , John D. Fraser، نويسنده , , Daniel P. Furkert، نويسنده , , Patrick D. O’Connor، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
7
From page
995
To page
1001
Abstract
A short convergent synthesis of the fungal metabolites cephalosporolides E and F is reported. The key step makes use of a chelation-controlled Mukaiyama aldol reaction to access the key acyclic spiroacetal precursor with the required syn stereochemistry.
Keywords
Mukaiyama aldol reaction , Cephalosporolide , Total synthesis , Natural products
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1102913
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