Title of article :
A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2-ones and thiones
Author/Authors :
Zhanxiong Fang، نويسنده , , Yulin Lam، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2-ones and thiones was developed. The reaction involves a one-pot reaction between oxalacetic acid, thiourea/urea, and aldehyde under microwave irradiation and provides the products in good yields and much shorter reaction times.
Keywords :
Microwave reaction , Biginelli reaction , multicomponent reaction , Chemoselectivity , Cyclocondensation
Journal title :
Tetrahedron
Journal title :
Tetrahedron
