Author/Authors :
Zhenlu Shen، نويسنده , , Xiaofei He، نويسنده , , Jialiang Dai، نويسنده , , Weimin Mo، نويسنده , , Baoxiang Hu، نويسنده , , Nan Sun، نويسنده , , Xinquan Hu، نويسنده ,
Abstract :
An efficient direct amination of quinazolin-4(3H)-ones has been developed. Treatment of quinazolin-4(3H)-ones with HCCP, DIPEA, and N-contained nucleophiles in acetonitrile could be able to form the corresponding 4-aminoquinazoline derivatives. Under the optimal reaction conditions, the amination products were achieved in good yields.
Keywords :
Amination , Quinazolin-4(3H)-ones , 4-Aminoquinazolines , Hexachlorocyclotriphosphazene
