Title of article :
Synthesis of fluorinated analogues of the immunosuppressive drug FTY720
Author/Authors :
Rebecca Y.Y. Ko، نويسنده , , John C.K. Chu، نويسنده , , Pauline Chiu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Four fluorinated derivatives of the immunosuppressive drug FTY720 were synthesized by a convergent strategy, using the Sonogashira coupling as the key reaction to assemble the two major fragments.
Keywords :
Immunosuppressive agent , FTY720 , Fluorinated drugs , Sonogashira coupling
Journal title :
Tetrahedron
Journal title :
Tetrahedron