Title of article
A Practical Diastereoselective Synthesis of syn-(alpha)-Hydroxyaminonitriles
Author/Authors
Leclerc، Eric نويسنده , , Abdillah، Fatoumia نويسنده , , Almeras، Loic نويسنده , , Mangeney، Pierre نويسنده , , Vrancken، Emmanuel نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-1032
From page
1033
To page
0
Abstract
An efficient and practical one pot two-step synthesis of syn-(alpha)hydroxyaminonitriles through an acylation-diastereoselective reduction sequence from lithiated (alpha)-aminonitrile is achieved.
Keywords
amino alcohols , reduction , acyl cyanide , dynamic kinetic resolution , diastereoselectivity
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110321
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