Title of article :
Enantioselective total synthesis of macrosphelides A and E
Author/Authors :
Kavirayani R. Prasad، نويسنده , , Phaneendra Gutala، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Enantioselective synthesis of 16-membered trilactone macrolides, macrosphelide A and E from (S)-lactic acid is described. Key features of the synthesis include the utility of a hitherto unexplored β-ketophosphonate derived from lactic acid and Yamaguchi lactonization leading to the title compounds.
Keywords :
macrosphelides , Total synthesis , Lactic acid , macrolactone
Journal title :
Tetrahedron
Journal title :
Tetrahedron
