Title of article
Six new monoterpenoid indole alkaloids from the aerial part of Gelsemium elegans
Author/Authors
Sheng Ouyang، نويسنده , , Lei Wang، نويسنده , , Qingwen Zhang، نويسنده , , Guocai Wang ، نويسنده , , Ying Wang، نويسنده , , Xiaojun Huang and Xiaodong Yuan، نويسنده , , Xiaoqi Zhang، نويسنده , , Ren-Wang Jiang، نويسنده , , Xinsheng Yao، نويسنده , , Chun-Tao Che، نويسنده , , Wen-Cai Ye، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
7
From page
4807
To page
4813
Abstract
Six new monoterpenoid indole alkaloids along with four known analogues were isolated from the aerial part of Gelsemium elegans. Their structures with absolute configurations were elucidated by NMR, HRESIMS, X-ray diffraction, CD spectra, and molecular modeling calculation. Among them, gelselenidine (1) is a new gelsedine-type alkaloid with a 2,3-epoxybutane unit. Gelseziridine (2) is the first example of monoterpenoid indole alkaloids with an oxaziridine residue. Compounds 6 and 7 are a pair of N4 epimers of humantenine N4-oxide. A plausible biogenetic pathway for compounds 1–4 was also proposed.
Keywords
Gelselenidine , Gelseziridine , Monoterpenoid alkaloid , Gelsemium elagans , oxindole alkaloid
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103376
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