Title of article
Microwave-mediated ‘click-chemistry’ synthesis of glycoporphyrin derivatives and in vitro photocytotoxicity for application in photodynamic therapy
Author/Authors
Guillaume Garcia، نويسنده , , Delphine Naud-Martin، نويسنده , , Danièle Carrez، نويسنده , , Alain Croisy، نويسنده , , Philippe Maillard، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
9
From page
4924
To page
4932
Abstract
In this paper, we report the synthesis of a series of porphyrins, designed as photodynamic therapy (PDT) agents, substituted by three glycosyl units linked by a triazole group to chromophore in the aim to target tumor cells overexpressing lectin-type membrane receptors, by ‘click-chemistry’ under microwave heating.
Keywords
Porphyrin , Carbohydrate , Photodynamic therapy , Click-chemistry , Microwave-assisted synthesis , Phototoxicity
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103395
Link To Document