Title of article
3-Acylindoles as versatile starting materials for pyridine ring annulation: synthesis of 1-deazapurine isosteres
Author/Authors
Ingo Knepper، نويسنده , , Viktor O. Iaroshenko، نويسنده , , Marcelo Vilches-Herrera، نويسنده , , Lutz Domke، نويسنده , , Satenik Mkrtchyan، نويسنده , , Muhammad Zahid، نويسنده , , Alexander Villinger، نويسنده , , Peter Langer، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
11
From page
5293
To page
5303
Abstract
The reaction of electron-rich aminoheterocycles with 3-acyl- and 3-formylindoles results in indole ring opening and cyclocondensation to give heteroannulated pyridines, which can be regarded as purine isosteres. The transformations reported herein represent rare examples of domino reactions, which include the cleavage of an indole moiety.
Keywords
1-Deazapurine isosteres , Cyclocondensation , Pyridine ring annulation , Regioselectivity , 3-Acylindoles
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103435
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