Title of article :
I-MCR-Ullmann cascade toward furo[2,3-b]indole scaffold
Author/Authors :
Xu Zhu، نويسنده , , Xiaoping Xu، نويسنده , , Chang Sun، نويسنده , , Tao Chen، نويسنده , , Zhiliang Shen، نويسنده , , Shun-Jun Ji، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
An efficient method for the construction of furo[2,3-b]indole derivatives 5 via an isocyanide-based multicomponent reaction (I-MCR) and a copper-catalyzed intramolecular Ullmann reaction sequence was described. This two-step sequence can be performed in a one-pot manner to produce the desired product 5 in moderate to good yield (up to 90%).
Keywords :
Furan , Copper catalysis , Intramolecular Ullmann coupling , Indole , Isocyanide-based multicomponent reaction (I-MCR) , One-pot reaction
Journal title :
Tetrahedron
Journal title :
Tetrahedron
