Author/Authors :
Tatsuya Shirahata، نويسنده , , Asami Kojima، نويسنده , , Satoko Teruya، نويسنده , , Jun-ichi Matsuo، نويسنده , , Masaki Yokoyama، نويسنده , , Shogo Unagiike، نويسنده , , Toshiaki Sunazuka، نويسنده , , Kazuishi Makino، نويسنده , , Eisuke Kaji، نويسنده , , Satoshi Omura، نويسنده , , Yoshinori Kobayashi، نويسنده ,
Abstract :
An efficient sequential one-pot glycosylation has been developed with glycosyl trichlorocarbamate and trichloroacetate activated by the same Lewis acid and enabled by a change in reaction temperature. The αα-selective glycosylation was achieved using glucose, galactose, and mannose substrates after investigation into the reactivities of the two types of glycosyl donors. Sequential one-pot dehydrative glycosylation, including in situ preparation of glycosyl donors followed by generation of two glycosyl bonds, provided three types of trisaccharide.
