Title of article :
Cell differentiation inducers from a marine sponge Biemna sp.
Author/Authors :
Reiko Ueoka، نويسنده , , Yuji Ise، نويسنده , , Shigeru Okada، نويسنده , , Shigeki Matsunaga، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Two pyridoacridines closely related to the known isocystodamine were isolated from the marine sponge Biemna sp. together with isocystodamine. Their structures were determined on the basis of spectroscopic data. They induce the erythroid differentiation of human leukemia K562 cells with an ED50 value of 5 nM each.
Keywords :
pyridoacridine , NMR , Isolation , Sponge , Cell differentiation
Journal title :
Tetrahedron
Journal title :
Tetrahedron
