Title of article :
The efficient synthesis of 2-arylpyrimidine acyclic nucleoside phosphonates using Liebeskind–Srogl cross-coupling reaction
Author/Authors :
Petra B?ehov?، نويسنده , , Michal ?esnek، نويسنده , , Martin Dra??nsk?، نويسنده , , Anton?n Hol?، نويسنده , , Zlatko Janeba، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A series of novel acyclic nucleoside phosphonates with various aryls attached to the C-2 position of the pyrimidine moiety has been prepared using the Liebeskind–Srogl cross-coupling protocol. The reactions of highly functionalised 2-(methylsulfanyl)pyrimidines with various arylboronic acids were studied and optimised.
Keywords :
Liebeskind–Srogl cross-coupling , acyclic nucleoside phosphonates , Pyrimidines , arylboronic acids , Microwave
Journal title :
Tetrahedron
Journal title :
Tetrahedron
