Title of article
Nickel chloride-catalyzed one-pot three-component synthesis of pyrazolophthalazinyl spirooxindoles
Author/Authors
Xiaonan Zhang، نويسنده , , Yong-Xiao Li، نويسنده , , Zhan-hui Zhang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
7426
To page
7430
Abstract
A direct and efficient approach for the preparation of pyrazolophthalazinyl spirooxindoles has been developed through one-pot three-component reaction of easily available isatin, malononitrile or cyanoacetic ester, and phthalhydrazide catalyzed by nickel chloride in polyethylene glycol 600. Desired products were obtained in high to excellent yields using a simple workup procedure.
Keywords
One-pot , Polyethylene glycol , multicomponent reaction , Nickel chloride , Pyrazolophthalazinyl spirooxindoles
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103682
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