Title of article
Regioselective iodination of chlorinated aromatic compounds using silver salts
Author/Authors
Sudhir N. Joshi، نويسنده , , Sandhya M. Vyas، نويسنده , , Huimin Wu، نويسنده , , Michael W. Duffel، نويسنده , , Sean Parkin، نويسنده , , Hans-Joachim Lehmler، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
9
From page
7461
To page
7469
Abstract
The iodination of chlorinated aromatic compounds using Ag2SO4/I2, AgSbF6/I2, AgBF4/I2, and AgPF6/I2 offers access to iodoarenes that are valuable intermediates in organic synthesis. Specifically, iodination of phenols, anisoles, and anilines with a 3,5-dichloro substitution pattern preferentially yielded the ortho, para, and para iodinated product, respectively. In the case of chlorobenzene and 3-chlorotoluene, AgSbF6/I2, AgBF4/I2, and AgPF6/I2, but not Ag2SO4/I2, selectively introduced the iodine in para position to the chlorine substituent.
Keywords
3-Chlorotoluene , Non-coordinating ions , Anisole , Aniline , Silver sulfate , Silver hexafluoroantimonate , Silver hexafluorophosphate , Phenol , Chlorobenzene , Silver tetrafluoroborate
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103685
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