• Title of article

    Quinidine thiourea-catalyzed enantioselective synthesis of β-nitrophosphonates: beneficial effects of molecular sieves

  • Author/Authors

    Santhi Abbaraju، نويسنده , , Mayur Bhanushali، نويسنده , , Cong-Gui Zhao، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2011
  • Pages
    6
  • From page
    7479
  • To page
    7484
  • Abstract
    An efficient method for enantioselective synthesis of β-nitrophosphonates via the Michael addition of diphenyl phosphite to nitroalkenes using the readily available quinidine thiourea organocatalyst has been developed. The desired β-nitrophosphonates were obtained in good ee values. Molecular sieves were found to be crucial for achieving high reproducible yields in this reaction.
  • Keywords
    Nitrophosphonates , Organocatalyst , Thiourea , Enantioselective synthesis , Molecular sieves
  • Journal title
    Tetrahedron
  • Serial Year
    2011
  • Journal title
    Tetrahedron
  • Record number

    1103687