Title of article
Dihydronaphthalenones from endophytic fungus Fusarium sp. BCC14842
Author/Authors
Jittra Kornsakulkarn، نويسنده , , Kulvadee Dolsophon، نويسنده , , Nattawut Boonyuen، نويسنده , , Tanapong Boonruangprapa، نويسنده , , Pranee Rachtawee، نويسنده , , Samran Prabpai، نويسنده , , Palangpon Kongsaeree، نويسنده , , Chawanee Thongpanchang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
8
From page
7540
To page
7547
Abstract
Eleven new dihydronaphthalenones 1–11, together with five known compounds; 5-hydroxydihydrofusarubin C (12), javanicin, bostrycoidin, anhydrofusarubin, and 3-O-methylfusarubin, were isolated from the endophytic fungus Fusarium sp. . Structures were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. Javanicin, 3-O-methylfusarubin, compounds 3 and 7 exhibited antimycobacterial and cytotoxic activities. Javanicin also displayed antifungal activity with IC50 of 6.16 μg/mL, while compounds 2, 4, 5, 8, and 12 showed only cytotoxic activity.
Keywords
Dihydronaphthalenones , Endophytic fungi , Fusarium sp , Bioactive secondary metabolites
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103693
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