Title of article
A formal synthesis of valiolamine from myo-inositol
Author/Authors
Rajendra C. Jagdhane، نويسنده , , Mysore S. Shashidhar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
8
From page
7963
To page
7970
Abstract
An efficient formal synthesis of racemic valiolamine starting from readily available myo-inositol is reported. In all the synthetic steps only one regioisomer is formed, which circumvents laborious purification of products. Regioselective benzylation of myo-inositol orthoformate, super-hydride mediated deoxygenation of a cyclitol derivative and stereoselective addition of dichloromethyllithium to an inosose are the key reactions in the synthesis.
Keywords
Amino sugar , Carbohydrate , Natural product , Valiolamine , Inositol , Cyclitol
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103742
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