Title of article :
Three-component reaction for the C2-functionalization of 1-substituted imidazoles with acetylenic ketones and isocyanates
Author/Authors :
Chen-Yang Shen، نويسنده , , Shuying Cai، نويسنده , , Chi He، نويسنده , , Xufeng Lin، نويسنده , , Ping Lu، نويسنده , , Yanguang Wang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
An efficient method for the direct C2-amidation of 1-substituted imidazoles with acetylenic ketones and isocyanates is reported. This three-component procedure has the advantages of catalyst-free, operational simplicity, mild reaction conditions, and good to excellent yields.
Keywords :
Heterocycles , cascade reactions , Huisgen zwitterion , Imidazoles , Multicomponent reactions
Journal title :
Tetrahedron
Journal title :
Tetrahedron
