Title of article
Efficient access to novel hexahydro-chromene and tetrahydro-pyrano[2,3-d]pyrimidine-annulated benzo-δ-sultones via a domino Knöevenagel-hetero-Diels–Alder reaction in water
Author/Authors
Mehdi Ghandi، نويسنده , , Elham Mohammadimehr، نويسنده , , Masoud Sadeghzadeh، نويسنده , , Abolfazl Hasani Bozcheloei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
8
From page
8484
To page
8491
Abstract
An efficient catalyst-free, diastereosective synthesis of novel hexahydro-chromene and tetrahydro-pyrano[2,3-d]pyrimidine-annulated benzo-δ-sultones is described. A number of 2-formyl-4-phenyl (E)-2-phenylethenesulfonates were synthesized and underwent a one-pot domino Knöevenagel-hetero-Diels–Alder reaction, respectively, with dimedone and N,N-dimethylbarbituric acid in water, affording the desired products in moderate to excellent yields.
Keywords
domino reactions , Kn?evenagel-hetero-Diels–Alder(E)-2-Formylphenyl-2-phenylethenesulfonates , Hexahydrochromenes , Benzo-?-sultones , Tetrahydropyranopyrimidines
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103808
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