Title of article
One-pot three-component synthesis of functionalized spirolactones by means of reaction between aromatic ketones, dimethyl acetylenedicarboxylate, and N-heterocycles
Author/Authors
Malek Taher Maghsoodlou، نويسنده , , Sayyed Mostafa Habibi-Khorassani، نويسنده , , Abbas Moradi، نويسنده , , Nourallah Hazeri، نويسنده , , Amir Davodi، نويسنده , , Seyed Sajad Sajadikhah، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
8492
To page
8495
Abstract
A simple and convenient one-pot multi-component reaction has been described for the synthesis of functionalized spirolactones. This strategy demonstrated three-component reaction between aromatic ketones (11H-indeno[1,2-b]quinoxalin-11-one) and dimethyl acetylenedicarboxylate (DMAD) in the presence of N-heterocycles, such as pyridine, quinoline, and isoquinoline in CH2Cl2 at ambient temperature without use of any catalyst or activator.
Keywords
DMAD , multi-component reaction , N-Heterocycle , spirolactone
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103809
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