Title of article
An enantioselective route to pyrrolidines: removal of the chiral template from homochiral pyrroloimidazoles
Author/Authors
Raymond C.F. Jones، نويسنده , , Kevin J. Howard، نويسنده , , John S. Snaith، نويسنده , , Alexander J. Blake، نويسنده , , Wang-Shei Li، نويسنده , , Peter J. Steel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
12
From page
8925
To page
8936
Abstract
Two-step reductive removal of the chiral template from optically active pyrroloimidazoles, available from 1,3-dipolar cycloaddition of homochiral 4,5-dihydroimidazolium ylides, gives optically active substituted pyrrolidines. Selective manipulation of the substituents affords, e.g., naturally occurring and other optically active proline derivatives, and optically active pyrrolizidines and indolizidines.
Keywords
Pyrrolidine , Pyrroloimidazole , Enantioselective , Pyrrolizidine , indolizidine
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103864
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