Title of article
An efficient synthesis of d-ribo-C18-phytosphingosine and l-arabino-C18-phytosphingosine from d-fructose
Author/Authors
Ramu Sridhar Perali، نويسنده , , Suresh Mandava، نويسنده , , Sudharani Chalapala، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
8
From page
9283
To page
9290
Abstract
d-ribo-C18-phytosphingosine and l-arabino-C18-phytosphingosine were synthesised starting from commercially inexpensive d-fructose. Metal-mediated fragmentation and stereoselective reduction were used as key steps to provide the hydrophilic portion of d-ribo and l-arabino phytosphingosines. Grubbs’ cross-metathesis and hydrogenation allowed the incorporation of hydrophobic tail.
Keywords
Phytosphingosines , Sphingolipids , Olefin cross-metathesis , D-Fructose
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103894
Link To Document