Author/Authors :
Philip J. Parsons، نويسنده , , Stephen P.G. Rushton، نويسنده , , Raghava R. Panta، نويسنده , , Adrian J. Murray، نويسنده , , Martyn P. Coles، نويسنده , , Jason Lai، نويسنده ,
Abstract :
New approaches to the synthesis of kainic acid and its analogues are presented. Two distinctly different approaches are described; the former utilised an intermolecular nitrile oxide addition to a homochiral substrate to furnish epikainate models and the second utilised amino acid chemistry to secure kainic acid.
Keywords :
Excitatory amino acids , Ene-reaction , Isoxazolidinone , Nitrile oxide , kainate
