Title of article
Synthesis of optically active homotryptophan and its oxygen and sulfur analogues
Author/Authors
Koushik Goswami، نويسنده , , Sibasish Paul، نويسنده , , Sandesh T. Bugde، نويسنده , , Surajit Sinha، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
7
From page
280
To page
286
Abstract
d-Homotryptophan and its sulfur analogue have been synthesized by Sonogashira coupling between 3-iodoheteroarenes and ethynyloxazolidine followed by reduction of triple bond and oxidation of alcohol to acid. l-Homotryptophan and its oxygen analogue have been synthesized from silylated internal alkyne using Larock’s heteroannulation as the key reaction. The alkynyloxazolidines were synthesized from l-serine and l-glutamic acid, respectively.
Keywords
Unnatural amino acid , Alkynyloxazolidine , Sonogashira coupling , Larock’s heteroannulation , Homotryptophan
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104041
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