Title of article
Regioselective conversion of alkynes to 4-substituted and 3,4-disubstituted isoxazoles using titanium-catalyzed multicomponent coupling reactions
Author/Authors
Amila A. Dissanayake، نويسنده , , Aaron L. Odom، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
6
From page
807
To page
812
Abstract
Conditions have been developed for the regioselective synthesis of 4-substituted isoxazoles from terminal alkynes and 3,4-disubstituted isoxazoles from internal alkynes. The methodology involves a one-pot titanium-catalyzed multicomponent coupling reaction followed by simple hydroxylamine hydrochloride addition.
Keywords
isoxazoles , Titanium , alkyne , Multicomponent coupling , Heterocycles
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104105
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