Title of article
Synthesis of (−)-benzolactam-V8 by application of asymmetric aziridination
Author/Authors
Itsara Khantikaew، نويسنده , , Masato Takahashi، نويسنده , , Takuya Kumamoto، نويسنده , , Noriyuki Suzuki، نويسنده , , Tsutomu Ishikawa، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
878
To page
882
Abstract
(−)-Benzolactam-V8, an artificially-designed cyclic dipeptide with strong tumor-promoter activity, was synthesized from benzyl (S)-N-(2-formylphenyl)-N-methylvalinate by application of guanidinium ylide-participated asymmetric aziridination followed by the reductive ring-opening reaction of 3-arylaziridine-2-carboxylate formed.
Keywords
3-Arylaziridine-2-carboxylate , ring-opening reaction , (?)-Benzolactam-V8 , Asymmetric synthesis , Guanidinium ylide
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104115
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