Author/Authors :
Hubert H?ebabeck?، نويسنده , , Milan Dejmek، نويسنده , , Martin Dra??nsk?، نويسنده , , Michal ??la، نويسنده , , Pieter Leyssen، نويسنده , , Johan Neyts، نويسنده , , Martina Kaniakov?، نويسنده , , Jan Kr??ek، نويسنده , , Radim Nencka، نويسنده ,
Abstract :
Azanorbornylpurine derivatives were prepared by Mitsunobu reaction of appropriate hydroxyazanorbornane derivative with 6-chloropurine or construction of purine base at azanorbornylamines. The prepared target compounds were evaluated for antiviral activity and effect on neuronal and muscle nicotinic acetylcholine receptors.
Keywords :
Mitsunobu reaction , coxsackievirus , Hepatitis C virus , Azanorbornane , Purines , Neuronal nicotinic acetylcholine receptor
