Title of article
Concise synthesis of new bridged-nicotine analogues
Author/Authors
François Crestey، نويسنده , , Geert Hooyberghs، نويسنده , , Jesper L. Kristensen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
1417
To page
1421
Abstract
This study describes a very efficient strategy for the synthesis of two new bridged-nicotine analogues. Starting from either 4- or 3-chloropyridine the desired tricyclic ring systems are accessed in just three steps in 23% and 40% overall yield, respectively.
Keywords
Pyridine metallation , Bridged-nicotine analogue , Suzuki–Miyaura cross-coupling reaction , Nicotinic acetylcholine receptor , Intramolecular reductive amination
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104180
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