Title of article
Phosphites and diamidophosphites based on mono-ethers of BINOL: a comparison of enantioselectivity in asymmetric catalytic reactions
Author/Authors
Konstantin N. Gavrilov، نويسنده , , Sergey V. Zheglov، نويسنده , , Mariya N. Gavrilova، نويسنده , , Ivan M. Novikov، نويسنده , , Marina G. Maksimova، نويسنده , , Nikolay N. Groshkin، نويسنده , , Eugenie A. Rastorguev، نويسنده , , Vadim A. Davankov، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
9
From page
1581
To page
1589
Abstract
Novel P-monodentate phosphite-type ligands have been synthesized in one step from BINOL mono-tosylate and BINOL mono-(−)-menthylcarbonate. The use of these ligands provides up to 96% ee in Pd-catalyzed asymmetric allylic substitution of (E)-1,3-diphenylallyl acetate and up to 99% ee in Rh-catalyzed asymmetric addition of phenylboronic acid to cyclohex-2-enone. The influence of the structural modules such as the nature of phosphorus-containing ring or exocyclic substituent on the enantioselectivity is discussed.
Keywords
Asymmetric allylic substitution , Palladium , asymmetric addition , Diamidophosphites , Rhodium , Phosphites
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104200
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