Title of article :
Trifluoroacetylation of Amino Acids under Aqueous Conditions Using a Readily Prepared Non-Odoriferous Reagent
Author/Authors :
Hickey، Matthew R. نويسنده , , Nelson، Todd D. نويسنده , , Secord، Elizabeth A. نويسنده , , Allwein، Shawn P. نويسنده , , Kress، Michael H. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
The synthesis of S-dodecyltrifluorothioacetate and its application to trifluoroacetylation of amino acids under aqueous conditions are described. This reagent afforded good isolated yields (71-92%) of the N-trifluoroacetyl derivatives via an operationally simple and odor free procedure.
Keywords :
amino acids , Schotten-Baumann , trifluoroacetylation , Green chemistry , thioester
