Title of article
Synthesis of tertiary carbinamines
Author/Authors
Muthoni G. Kamau، نويسنده , , Lalgudi S. Harikrishnan، نويسنده , , Heather J. Finlay، نويسنده , , Jennifer X. Qiao، نويسنده , , Ji Jiang، نويسنده , , Michael A. Poss، نويسنده , , Mark E. Salvati، نويسنده , , Ruth R. Wexler، نويسنده , , R. Michael Lawrence، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
8
From page
2696
To page
2703
Abstract
An efficient synthesis of tertiary carbinamines using a one-pot, three-component reaction employing TMSCl activation of an intermediate imine salt followed by addition of an organometallic is described. An optimized second generation chiral synthesis of select tertiary carbinamines utilizing the Ellman sulfinamine was subsequently developed on a multi-gram scale and is also described.
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104324
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