Title of article
Buchwald-Hartwig Aminations of Aryl Chlorides: A Practical Protocol Based on Commercially Available Pd(0)-NHC Catalysts
Author/Authors
Gooben، L. J. نويسنده , , Paetzold، J. نويسنده , , Briel، O. نويسنده , , Rivas-Nass، A. نويسنده , , Karch، R. نويسنده , , Kayser، B. نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-274
From page
275
To page
0
Abstract
Commercially available, air- and water-stable naphthoquinone imidazolin-2-ylidene-palladium(0) complexes were found to be highly active one-component catalysts for the amination of aryl halides. With these very robust catalysts, the expensive bases Cs2CO3 or NaOt-Bu traditionally used can be replaced by KOH. A convenient reaction protocol has been developed for the coupling of a wide range of aryl chlorides with primary or secondary amines.
Keywords
carbene ligands , amination , aryl chlorides , Palladium
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110434
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