Title of article
Highly stereoselective synthesis of N-substituted π-conjugated phthalimides
Author/Authors
Piotr Pawlu?، نويسنده , , Adrian Franczyk، نويسنده , , J?drzej Walkowiak، نويسنده , , Grzegorz Hreczycho، نويسنده , , Maciej Kubicki*، نويسنده , , Bogdan Marciniec، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
7
From page
3545
To page
3551
Abstract
A new regio- and stereoselective synthesis of (E)-N-(2-arylvinyl)phthalimides as well as phthalimide-containing (E,E)-buta-1,3-dienes and (E)-but-1-en-3-ynes has been developed. The one-pot ruthenium-catalyzed silylative coupling/iododesilylation sequence provides (E)-N-(2-iodovinyl)phthalimide 1, which undergoes palladium-catalyzed Suzuki–Miyaura or Sonogashira cross-coupling to afford stereodefined highly π-conjugated phthalimides and functionalized dienimides containing phthalimide groups.
Keywords
Phthalimides , Silylative coupling , Iododesilylation , Sonogashira coupling , Suzuki–Miyaura coupling
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104424
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