Title of article
Access to original spirocyclic derivatives via inter- or intramolecular reaction mediated by manganese(III) acetate
Author/Authors
Ahlem Bouhlel، نويسنده , , Christophe Curti، نويسنده , , Michèle P. Bertrand، نويسنده , , Patrice Vanelle، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
9
From page
3596
To page
3604
Abstract
An easily reproducible protocol allowing inter- or intramolecular spirocyclization on β-dicarbonyl structures is described. This methodology could afford a wide variety of spirocyclic pharmacophores. As examples, highly substituted spirobenzophenanthridin-6(5H)-ones and spirolactones were synthesized. These scaffolds could be used for the design of many compounds exhibiting biological activities.
Keywords
manganese(III) acetate , Spirocyclic derivatives , Benzophenanthridinone , spirolactones
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104431
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