Title of article :
Formal Synthesis of (+)-Anatoxin-a by Asymmetric [2+2] Cycloaddition
Author/Authors :
Muniz، Mauro Neves نويسنده , , Kanazawa، Alice نويسنده , , Greene، Andrew E. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A formal asymmetric synthesis of (+)-anatoxin-a, a neurotoxic alkaloid from Anabaena flos aquae, has been achieved through a highly diastereoselective [2+2] cycloaddition of dichloroketene with a chiral enol ether.
Keywords :
N-acyliminium ion , asymmetric synthesis , Cycloaddition , chiral enol ether , dichloroketene