• Title of article

    2′-Fluoro-3-deazaaristeromycin

  • Author/Authors

    Chun Chen، نويسنده , , Wei Ye، نويسنده , , Chong Liu، نويسنده , , Stewart W. Schneller، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2012
  • Pages
    7
  • From page
    3908
  • To page
    3914
  • Abstract
    The carbocyclic nucleoside 3-deazaaristeromycin has shown biological promise but a library of its derivatives upon which to expand this property is lacking. To address this situation, the synthesis of the two diastereomers of 2′-fluoro-3-deazaaristeromycin is described in a multistep convergent process that calls upon d-ribose for construction of the cyclopentyl fluoro units.
  • Keywords
    carbocyclic nucleosides , Mitsunobu coupling , Grubbs reaction , DAST fluorination
  • Journal title
    Tetrahedron
  • Serial Year
    2012
  • Journal title
    Tetrahedron
  • Record number

    1104472