Title of article :
Asymmetric Synthesis of 1,2-Amino Alcohols Using tert-Butanesulfinimines as Chiral Auxiliary
Author/Authors :
Ko، Chang Hong نويسنده , , Jung، Doo Young نويسنده , , Kim، Min Kyun نويسنده , , Kim، Yong Hae نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Facile and highly stereoselective synthesis of 1,2-amino alcohols has been achieved by the addition of [(dimethylphenylsilyl) methyl] magnesium chloride to the tert-butanesulfinimines, followed by Fleming-Tamao oxidation of the silicon moiety.
Keywords :
Nucleophilic addition , Grignard reagents , enantioselective synthesis , tert-butanesulfinimine , amino alcohol
