Title of article
Nucleophilic difluoromethylation of Cdouble bond; length as m-dashN bonds in heterocycles with difluoromethyl silane reagents
Author/Authors
Weizhou Huang، نويسنده , , Chuanfa Ni، نويسنده , , Yanchuan Zhao، نويسنده , , Wei Zhang، نويسنده , , Alexander D. Dilman، نويسنده , , Jinbo Hu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
8
From page
5137
To page
5144
Abstract
An efficient and straightforward nucleophilic difluoromethylation of Cdouble bond; length as m-dashN bonds in heterocycles under the activation of alkylating agents has been developed. Cyclic iminium salts derived from dihydroisoquinolines, quinolines, and pyridines were successfully difluoromethylated with sulfur-based fluoroalkyl silanes affording a series of new difluoromethylated nitrogen-containing heterocyclic compounds.
Keywords
Nucleophilic reaction , Silane reagents , Fluoroalkylation , Fluorine chemistry , Heterocycles
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104615
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