Title of article :
A novel one-pot synthesis of 2-arylpyrazoloquinolinone derivatives
Author/Authors :
En-Chiuan Chang، نويسنده , , Ya-Lan Wen، نويسنده , , Chun-Hsi Chang، نويسنده , , Yun-Hwei Shen، نويسنده , , Shaw-Bing Wen، نويسنده , , Mou-Yung Yeh، نويسنده , , Fung Fuh Wong، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Two regioisomers of 2-arylpyrazolo[3,4-c]quinolin-4(5H)-ones and 2-arylpyrazolo[4,3-c]quinolin-4(5H)-ones were synthesized by utilizing 3-arylsydnones, ethyl 3-bromopropynoate, and 2-aminophenylboronic acid pinacol ester in presence of catalytic agent Pd(PPh3)4. This efficient one-pot synthesis methodology involved 1,3-dipolar cycloaddition, Suzuki coupling reaction, and intramolecular cyclization three sequence steps.
Keywords :
4-c]quinolin-4(5H)-ones , 3-c]quinolin-4(5H)-ones , 3-Aryl sydnone , 1 , 3-dipolar cycloaddition , Adenosine receptor , Suzuki coupling reaction
Journal title :
Tetrahedron
Journal title :
Tetrahedron
