• Title of article

    Short and Efficient Synthesis of Cadiolide B

  • Author/Authors

    Boukouvalas، John نويسنده , , Pouliot، Martin نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    -342
  • From page
    343
  • To page
    0
  • Abstract
    The first synthesis of cadiolide B has been achieved in 6 steps and 42% overall yield from 4-bromo-2(5H)-furanone. The pathway involves sequential, regiocontrolled introduction of the three furanone substituents by means of aldol reactions and Suzuki cross coupling.
  • Keywords
    total synthesis , lactones , aldol reaction , 2-furanolates , cross coupling
  • Journal title
    Synlett
  • Serial Year
    2005
  • Journal title
    Synlett
  • Record number

    110472