Microwave-assisted, montmorillonite K-10 catalyzed three-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones under solvent-free conditions

An efficient, rapid, and green synthesis of 2H-indazolo[2,1-b]phthalazine-triones has been accomplished under solvent-free conditions by the reaction of phthalhydrazide, aldehydes and 5,5-dimethylcyclohexane-1,3-dione. This approach exploits the synthetic potential of microwave irradiation and Montmorillonite K-10 combination and offers many advantages, such as excellent product yields, shorter reaction time, reusable catalyst, easy isolation of products, and environmentally benign reaction conditions.