Title of article :
Access to 2-alkyl chromanones via a conjugate addition approach
Author/Authors :
Louise A. Stubbing، نويسنده , , Freda F. Li، نويسنده , , Daniel P. Furkert، نويسنده , , Vittorio E. Caprio، نويسنده , , Margaret A. Brimble، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The introduction of alkyl substituents at C-2 of chromanones via conjugate addition of silyl enol ethers to a variety of chromenones is reported. In most cases racemic 2-alkyl chromanones were obtained in good yield in the presence of TMSOTf. The copper(II)-promoted conjugate addition of silyl enol ethers to chromenones was also carried out, albeit in low yields and no selectivity. Reliable syntheses of the chromenones via acylation of the corresponding β-diketo-compounds are also described.
Keywords :
Chromenones , chromanones , Conjugate addition
Journal title :
Tetrahedron
Journal title :
Tetrahedron