Title of article
Synthesis of fluorinated N-aminoaziridines: access to new CF3-peptidomimetics
Author/Authors
Bertrand Schweitzer-Chaput، نويسنده , , Massaba Keita، نويسنده , , Thierry Milcent، نويسنده , , Sandrine Ongeri، نويسنده , , Benoît Crousse، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
7
From page
7028
To page
7034
Abstract
A series of fluorinated N-aminoaziridines have been synthesized by the PhI(OAc)2-mediated aziridination procedure. The reaction was carried out with various protected hydrazides and fluorinated alkenes. The reaction was extended to alkenes bearing an amino acid and the ring opening of the CF3–N-aminoaziridines has been investigated.
Keywords
Amino acids , N-Amino aziridine , Fluorine , Peptidomimetic , Iodobenzene diacetate
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104833
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