Title of article
Regioselective N9 alkylation of purine rings assisted by β-cyclodextrin
Author/Authors
Qian Zhang، نويسنده , , Gang Cheng، نويسنده , , Yong-Zhen Huang، نويسنده , , Guirong Qu، نويسنده , , Hong-Ying Niu، نويسنده , , Hai-Ming Guo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
7822
To page
7826
Abstract
Under the assistance of β-cyclodextrin, purine was effectively alkylated at N9 together with up to 99% conversion and good to excellent yield using water as the solvent. High regioselectivity-N9/N7 selectivity>99:1 was attributed to the β-cyclodextrin cavity blocked the N7 of purines ring.
Keywords
Purine , Alkylation , Selectivity , ?-Cyclodextrin
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104932
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