Title of article
Bromination of 4,6-dimethoxyindoles
Author/Authors
Peter S.R. Mitchell، نويسنده , , Ibrahim F. Sengul، نويسنده , , Hakan Kandemir، نويسنده , , Stephen J. Nugent، نويسنده , , Rui Chen، نويسنده , , Paul K. Bowyer، نويسنده , , Naresh Kumar، نويسنده , , David StC. Black، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
9
From page
8163
To page
8171
Abstract
The bromination of activated 4,6-dimethoxyindoles can be carried out effectively provided that an electron-withdrawing group is also present. Thus the range of products includes 2-bromo-7-formyl or 2-bromo-7-acetylindoles 13a–c and 16, 7-bromo-2-acetylindole 21, 2,5-dibromo-7-acetylindole 17, 2,5-dibromo-N-sulfonylindole 27, and 2,7-dibromo-N-acetylindole 24. Acetyl and sulfonyl protecting groups on nitrogen can be removed to give 2-bromoindoles 28a–b, 2,5-dibromoindole 29, and 2,7-dibromoindole 4.
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104968
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