• Title of article

    β-Lactam-synthon-interceded diastereoselective synthesis of functionally enriched thioxo-imidazolidines, imidazolidin-2-ones, piperazine-5,6-diones and 4,5-dihydroimidazoles

  • Author/Authors

    Vishu Mehra، نويسنده , , Pardeep Singh، نويسنده , , Vipan Kumar، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2012
  • Pages
    8
  • From page
    8395
  • To page
    8402
  • Abstract
    The manuscript explicates simple and convenient protocols for the diastereoselective synthesis of functionally decorated thioxo-imidazolidines, imidazolidin-2-ones, piperazine-5,6-diones and 4,5-dihydroimidazoles using β-lactam synthon approach with an extension towards one-pot synthesis. Since the developed methodology does not employ either the use of Lewis acid conditions or Pd-catalyzed customary procedures, the developed route can be easily modulated for the synthesis of functionalized imidazoles with acid-sensitive functionalities and do not suffer from typical intricacies associated with conventional methods.
  • Keywords
    4 , ?-Lactam synthon approach , Thioxo-imidazolines , 5-Dihydroimidazoles , Imidazolidine-2-ones , Piperazine-5 , 6-diones
  • Journal title
    Tetrahedron
  • Serial Year
    2012
  • Journal title
    Tetrahedron
  • Record number

    1104996